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-Structure paper
Title | Enhancing the Activity of a Protein by Stereospecific Unfolding: CONFORMATIONAL LIFE CYCLE OF INSULIN AND ITS EVOLUTIONARY ORIGINS. |
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Journal, issue, pages | J. Biol. Chem., Vol. 284, Page 14586-14596, Year 2009 |
Publish date | Sep 29, 2008 (structure data deposition date) |
![]() | Hua, Q.X. / Xu, B. / Huang, K. / Hu, S.Q. / Nakagawa, S. / Jia, W. / Wang, S. / Whittaker, J. / Katsoyannis, P.G. / Weiss, M.A. |
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Methods | NMR (solution) |
Structure data | ![]() PDB-2k91: ![]() PDB-2k9r: |
Source |
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![]() | HORMONE / INSULIN / MUTANT / Carbohydrate metabolism / Cleavage on pair of basic residues / Diabetes mellitus / Disease mutation / Glucose metabolism / Pharmaceutical / Secreted |