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TitleEngineering a stable and selective peptide blocker of the Kv1.3 channel in T lymphocytes
Journal, issue, pagesMol. Pharmacol., Vol. 75, Page 762-773, Year 2009
Publish dateOct 9, 2008 (structure data deposition date)
AuthorsPennington, M.W. / Beeton, C. / Galea, C.A. / Smith, B.J. / Chi, V. / Monaghan, K.P. / Garcia, A. / Rangaraju, S. / Giuffrida, A. / Plank, D. ...Pennington, M.W. / Beeton, C. / Galea, C.A. / Smith, B.J. / Chi, V. / Monaghan, K.P. / Garcia, A. / Rangaraju, S. / Giuffrida, A. / Plank, D. / Crossley, G. / Nugent, D. / Khaytin, I. / Lefievre, Y. / Peshenko, I. / Dixon, C. / Chauhan, S. / Orzel, A. / Inoue, T. / Hu, X. / Moore, R.V. / Norton, R.S. / Chandy, K.G.
External linksMol. Pharmacol. / PubMed:19122005
MethodsNMR (solution)
Structure data

PDB-2k9e:
NMR Solution Structure for ShK-192: A Potent KV1.3-Specific Immunosuppressive Polypeptide
Method: SOLUTION NMR

Source
  • stichodactyla helianthus (sea anemone)
KeywordsTOXIN / Protein / Ionic channel inhibitor / Nematocyst / Neurotoxin / Potassium channel inhibitor / Secreted

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