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Structure paper

TitleStructures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms.
Journal, issue, pagesJ. Mol. Biol., Vol. 368, Page 691-705, Year 2007
Publish dateFeb 12, 2007 (structure data deposition date)
AuthorsRosettani, P. / Knapp, S. / Vismara, M.G. / Rusconi, L. / Cameron, A.D.
External linksJ. Mol. Biol. / PubMed:17368478
MethodsX-ray diffraction
Resolution1.7 - 2.4 Å
Structure data

PDB-2jgb:
Structure of human eIF4E homologous protein 4EHP with m7GTP
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-2jgc:
Structure of the human eIF4E homologous protein, 4EHP without ligand bound
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-MGT:
7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSLATION / PHOSPHORYLATION / INITIATION FACTOR / 4EHP / EIF4E / RNA-BINDING / ACETYLATION / CAP-BINDING / EUKARYOTIC INITIATION FACTOR / PROTEIN SYNTHESIS INHIBITOR / PROTEIN BIOSYNTHESIS / TRANSLATION REGULATION

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