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TitleFunctional Studies of Active-Site Mutants from Drosophila Melanogaster Deoxyribonucleoside Kinase. Investigations of the Putative Catalytic Glutamate- Arginine Pair and of Residues Responsible for Substrate Specificity.
Journal, issue, pagesFEBS J., Vol. 274, Page 1542-, Year 2007
Publish dateJan 3, 2007 (structure data deposition date)
AuthorsEgeblad-Welin, L. / Sonntag, Y. / Eklund, H. / Munch-Petersen, B.
External linksFEBS J. / PubMed:17302737
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-2jcs:
Active site mutant of dNK from D. melanogaster with dTTP bound
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-TTP:
THYMIDINE-5'-TRIPHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • drosophila melanogaster (fruit fly)
KeywordsTRANSFERASE / KINASE / ATP-BINDING / DNA SYNTHESIS / NUCLEOTIDE- BINDING / DEOXYRIBONUCLEOSIDE KINASE

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