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Structure paper

TitleDisruption of methylarginine metabolism impairs vascular homeostasis.
Journal, issue, pagesNat. Med., Vol. 13, Page 198-203, Year 2007
Publish dateNov 29, 2006 (structure data deposition date)
AuthorsLeiper, J. / Nandi, M. / Torondel, B. / Murray-Rust, J. / Malaki, M. / O'Hara, B. / Rossiter, S. / Anthony, S. / Madhani, M. / Selwood, D. ...Leiper, J. / Nandi, M. / Torondel, B. / Murray-Rust, J. / Malaki, M. / O'Hara, B. / Rossiter, S. / Anthony, S. / Madhani, M. / Selwood, D. / Smith, C. / Wojciak-Stothard, B. / Rudiger, A. / Stidwill, R. / McDonald, N.Q. / Vallance, P.
External linksNat. Med. / PubMed:17273169
MethodsX-ray diffraction
Resolution2 - 2.3 Å
Structure data

PDB-2jai:
DDAH1 complexed with citrulline
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-2jaj:
DDAH1 complexed with L-257
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-CIR:
CITRULLINE

ChemComp-HOH:
WATER

ChemComp-D20:
N~5~-{IMINO[(2-METHOXYETHYL)AMINO]METHYL}-L-ORNITHINE

Source
  • homo sapiens (human)
KeywordsHYDROLASE / DDAH / NITRIC OXIDE SYNTHASE INHIBITOR

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