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Structure paper

TitleCrystal Structure of Human Inosine Triphosphatase. Substrate Binding and Implication of the Inosine Triphosphatase Deficiency Mutation P32T.
Journal, issue, pagesJ. Biol. Chem., Vol. 282, Page 3182-, Year 2007
Publish dateDec 22, 2005 (structure data deposition date)
AuthorsStenmark, P. / Kursula, P. / Flodin, S. / Graslund, S. / Landry, R. / Nordlund, P. / Schuler, H.
External linksJ. Biol. Chem. / PubMed:17138556
MethodsX-ray diffraction
Resolution1.09 - 2.8 Å
Structure data

PDB-2car:
Crystal Structure Of Human Inosine Triphosphatase
Method: X-RAY DIFFRACTION / Resolution: 1.09 Å

PDB-2j4e:
THE ITP COMPLEX OF HUMAN INOSINE TRIPHOSPHATASE
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-ITT:
INOSINE 5'-TRIPHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-POP:
PYROPHOSPHATE 2-

ChemComp-IMP:
INOSINIC ACID

Source
  • homo sapiens (human)
KeywordsHYDROLASE / INOSINE TRIPHOSPHATE PYROPHOSPHOHYDROLASE / INOSINE TRIPHOSPHATASE DEFICIENCY / ITP / IMP / DISEASE MUTATION / NUCLEOTIDE METABOLISM

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