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Title3,4,5-Trisubstituted Isoxazoles as Novel Ppardelta Agonists. Part 2
Journal, issue, pagesBioorg. Med. Chem. Lett., Vol. 16, Page 5488-, Year 2006
Publish dateAug 8, 2006 (structure data deposition date)
AuthorsEpple, R. / Azimioara, M. / Russo, R. / Xie, Y. / Wang, X. / Cow, C. / Wityak, J. / Karanewsky, D. / Bursulaya, B. / Kreusch, A. ...Epple, R. / Azimioara, M. / Russo, R. / Xie, Y. / Wang, X. / Cow, C. / Wityak, J. / Karanewsky, D. / Bursulaya, B. / Kreusch, A. / Tuntland, T. / Gerken, A. / Iskandar, M. / Saez, E. / Seidel, H.M. / Tian, S.S.
External linksBioorg. Med. Chem. Lett. / PubMed:16931011
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-2j14:
3,4,5-Trisubstituted Isoxazoles as Novel PPARdelta Agonists: Part2
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-GNI:
(3-{4-[2-(2,4-DICHLORO-PHENOXY)-ETHYLCARBAMOYL]-5-PHENYL-ISOXAZOL-3-YL}-PHENYL)-ACETIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / NUCLEAR RECEPTOR FOLD / TRANSCRIPTION REGULATION / PPAR / ZINC / RECEPTOR / ACTIVATOR / FATTY ACIDS / NUCLEAR PROTEIN / ALTERNATIVE SPLICING / ZINC-FINGER / DNA-BINDING / METAL-BINDING

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