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-Structure paper
Title | Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach. |
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Journal, issue, pages | Eur. J. Hum. Genet., Vol. 16, Page 820-832, Year 2008 |
Publish date | Oct 7, 2006 (structure data deposition date) |
![]() | Tischkowitz, M. / Hamel, N. / Carvalho, M.A. / Birrane, G. / Soni, A. / van Beers, E.H. / Joosse, S.A. / Wong, N. / Novak, D. / Quenneville, L.A. ...Tischkowitz, M. / Hamel, N. / Carvalho, M.A. / Birrane, G. / Soni, A. / van Beers, E.H. / Joosse, S.A. / Wong, N. / Novak, D. / Quenneville, L.A. / Grist, S.A. / Nederlof, P.M. / Goldgar, D.E. / Tavtigian, S.V. / Monteiro, A.N. / Ladias, J.A. / Foulkes, W.D. |
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Methods | X-ray diffraction |
Resolution | 3.6 Å |
Structure data | ![]() PDB-2ing: |
Chemicals | ![]() ChemComp-CO: ![]() ChemComp-SO4: |
Source |
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![]() | DNA BINDING PROTEIN / Zinc-finger / DNA-binding / DNA repair / Disease mutation / Phosphorylation |