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Structure paper

TitleInfluence of the target base partner on the methylation rate of the adenine-specific DNA methyltransferase M.TaqI
Journal, issue, pagesTo be Published
Publish dateSep 25, 2006 (structure data deposition date)
AuthorsLenz, T. / Scheidig, A.J. / Weinhold, E.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.61 - 2.1 Å
Structure data

PDB-2ih2:
Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing 5-methylpyrimidin-2(1H)-one at the target base partner position
Method: X-RAY DIFFRACTION / Resolution: 1.61 Å

PDB-2ih4:
Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing pyrrolo-dC at the target base partner position
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-2ih5:
Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing an abasic site analog at the target base partner position
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-NEA:
5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE

ChemComp-HOH:
WATER

Source
  • thermus aquaticus (bacteria)
KeywordsTRANSFERASE/DNA / DNA / DNA methyltransferase / target base partner / 5-methylpyrimidin-2(1H)-one / base flipping / nucleotide flipping / TRANSFERASE-DNA COMPLEX / pyrrolo-dC / abasic site analog

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