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-Structure paper
Title | Novel thiazolones as HCV NS5B polymerase allosteric inhibitors: Further designs, SAR, and X-ray complex structure. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 17, Page 63-67, Year 2007 |
Publish date | Aug 14, 2006 (structure data deposition date) |
![]() | Yan, S. / Larson, G. / Wu, J.Z. / Appleby, T. / Ding, Y. / Hamatake, R. / Hong, Z. / Yao, N. |
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Methods | X-ray diffraction |
Resolution | 2.2 Å |
Structure data | ![]() PDB-2i1r: |
Chemicals | ![]() ChemComp-VXR: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / hcv / ns5b / viral RNA-directed RNA Polymerase / RdRP / allosteric inhibitor / HCV inhibitor complex |