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IF

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Structure paper

TitleA general strategy for creating
Journal, issue, pagesChem. Biol., Vol. 13, Page 779-786, Year 2006
Publish dateJun 29, 2006 (structure data deposition date)
AuthorsOkram, B. / Nagle, A. / Adrian, F.J. / Lee, C. / Ren, P. / Wang, X. / Sim, T. / Xie, Y. / Xia, G. / Spraggon, G. ...Okram, B. / Nagle, A. / Adrian, F.J. / Lee, C. / Ren, P. / Wang, X. / Sim, T. / Xie, Y. / Xia, G. / Spraggon, G. / Warmuth, M. / Liu, Y. / Gray, N.S.
External linksChem. Biol. / PubMed:16873026
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-2hiw:
Crystal Structure of Inactive Conformation Abl Kinase Catalytic Domain Complexed with Type II Inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-7MP:
7-AMINO-1-METHYL-3-(2-METHYL-5-{[3-(TRIFLUOROMETHYL)BENZOYL]AMINO}PHENYL)-2-OXO-2,3-DIHYDROPYRIMIDO[4,5-D]PYRIMIDIN-1-IUM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / kinase domain

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