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-Structure paper
Title | Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 16, Page 4252-4256, Year 2006 |
Publish date | May 13, 2006 (structure data deposition date) |
![]() | Amarasinghe, K.K. / Evdokimov, A.G. / Xu, K. / Clark, C.M. / Maier, M.B. / Srivastava, A. / Colson, A.O. / Gerwe, G.S. / Stake, G.E. / Howard, B.W. ...Amarasinghe, K.K. / Evdokimov, A.G. / Xu, K. / Clark, C.M. / Maier, M.B. / Srivastava, A. / Colson, A.O. / Gerwe, G.S. / Stake, G.E. / Howard, B.W. / Pokross, M.E. / Gray, J.L. / Peters, K.G. |
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Methods | X-ray diffraction |
Resolution | 1.65 - 2.3 Å |
Structure data | ![]() PDB-2h02: ![]() PDB-2h03: ![]() PDB-2h04: |
Chemicals | ![]() ChemComp-2UN: ![]() ChemComp-HOH: ![]() ChemComp-CL: ![]() ChemComp-MG: ![]() ChemComp-3UN: ![]() ChemComp-4UN: |
Source |
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![]() | HYDROLASE / protein tyrosine phosphatase / WPD-loop / sulfamic acid / phosphatase / inhibitor / drug design |