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-Structure paper
Title | An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor. |
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Journal, issue, pages | Cell(Cambridge,Mass. ), Vol. 125, Page 1137-1149, Year 2006 |
Publish date | Apr 25, 2006 (structure data deposition date) |
![]() | Zhang, X. / Gureasko, J. / Shen, K. / Cole, P.A. / Kuriyan, J. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.6 - 2.8 Å |
Structure data | ![]() PDB-2gs2: ![]() PDB-2gs6: ![]() PDB-2gs7: |
Chemicals | ![]() ChemComp-HOH: ![]() ChemComp-CL: ![]() ChemComp-112: ![]() ChemComp-MG: ![]() ChemComp-IOD: ![]() ChemComp-ANP: |
Source |
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![]() | TRANSFERASE / EGFR / kinase / active / ATP-analog peptide conjugate / inactive / AMP-PNP |