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-Structure paper
Title | Platensimycin is a selective FabF inhibitor with potent antibiotic properties. |
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Journal, issue, pages | Nature, Vol. 441, Page 358-361, Year 2006 |
Publish date | Mar 23, 2006 (structure data deposition date) |
![]() | Wang, J. / Soisson, S.M. / Young, K. / Shoop, W. / Kodali, S. / Galgoci, A. / Painter, R. / Parthasarathy, G. / Tang, Y.S. / Cummings, R. ...Wang, J. / Soisson, S.M. / Young, K. / Shoop, W. / Kodali, S. / Galgoci, A. / Painter, R. / Parthasarathy, G. / Tang, Y.S. / Cummings, R. / Ha, S. / Dorso, K. / Motyl, M. / Jayasuriya, H. / Ondeyka, J. / Herath, K. / Zhang, C. / Hernandez, L. / Allocco, J. / Basilio, A. / Tormo, J.R. / Genilloud, O. / Vicente, F. / Pelaez, F. / Colwell, L. / Lee, S.H. / Michael, B. / Felcetto, T. / Gill, C. / Silver, L.L. / Hermes, J.D. / Bartizal, K. / Barrett, J. / Schmatz, D. / Becker, J.W. / Cully, D. / Singh, S.B. |
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Methods | X-ray diffraction |
Resolution | 2.29 - 2.85 Å |
Structure data | ![]() PDB-2gfv: ![]() PDB-2gfw: ![]() PDB-2gfx: ![]() PDB-2gfy: |
Chemicals | ![]() ChemComp-HOH: ![]() ChemComp-PMN: ![]() ChemComp-DAO: |
Source |
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![]() | TRANSFERASE / FabF; KASII; acyl-enzyme intermediate / FabF; KASII; ketoacyl synthase / FabF; KASII; ketoacyl synthase; platensimycin |