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Structure paper

TitleIdentification of Pyridinylpyrimidines as Inhibitors of Human Methionine Aminopeptidases.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 45, Page 3772-3775, Year 2006
Publish dateFeb 24, 2006 (structure data deposition date)
AuthorsHu, X. / Addlagatta, A. / Matthews, B.W. / Liu, J.O.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:16724298
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-2g6p:
Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with Pyridyl pyrimidine derivative
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-CO:
Unknown entry

ChemComp-K:
Unknown entry

ChemComp-HM2:
5-CHLORO-6-METHYL-N-(2-PHENYLETHYL)-2-PYRIDIN-2-YLPYRIMIDIN-4-AMINE

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / methionine aminopeptidase / pyridinyl pyrimidine

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