+Search query
-Structure paper
Title | Different poses for ligand and chaperone in inhibitor-bound Hsp90 and GRP94: implications for paralog-specific drug design. |
---|---|
Journal, issue, pages | J. Mol. Biol., Vol. 388, Page 1033-1042, Year 2009 |
Publish date | Nov 8, 2005 (structure data deposition date) |
![]() | Immormino, R.M. / Metzger, L.E. / Reardon, P.N. / Dollins, D.E. / Blagg, B.S. / Gewirth, D.T. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2 - 2.35 Å |
Structure data | ![]() PDB-2exl: ![]() PDB-2fxs: ![]() PDB-2gfd: |
Chemicals | ![]() ChemComp-GDM: ![]() ChemComp-PG4: ![]() ChemComp-1PE: ![]() ChemComp-HOH: ![]() ChemComp-RDA: ![]() ChemComp-GOL: |
Source |
|
![]() | CHAPERONE / GRP94 / gp96 / HSP90 / Bergerat fold / Endoplasmic reticulum / Geldanamycin / 17-AAG / HSP82 / HTPG / ligand / radicicol / radester / radamide |