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-Structure paper
Title | Enantiomer Discrimination Illustrated by the High Resolution Crystal Structures of Type 4 Phosphodiesterase |
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Journal, issue, pages | J. Med. Chem., Vol. 49, Page 1867-1873, Year 2006 |
Publish date | Jan 6, 2006 (structure data deposition date) |
Authors | Huai, Q. / Sun, Y. / Wang, H. / Macdonald, D. / Aspiotis, R. / Robinson, H. / Huang, Z. / Ke, H. |
External links | J. Med. Chem. / PubMed:16539372 |
Methods | X-ray diffraction |
Resolution | 2 - 2.03 Å |
Structure data | PDB-2fm0: PDB-2fm5: |
Chemicals | ChemComp-ZN: ChemComp-MG: ChemComp-M98: ChemComp-HOH: ChemComp-M99: |
Source |
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Keywords | HYDROLASE / PDE. enantiomer binding / inhibitor selectivity / cAMP signalling / PDE4 / L-869299 / enantiomer binding / cAMP signal |