+Search query
-Structure paper
Title | Conformation-assisted inhibition of protein-tyrosine phosphatase-1B elicits inhibitor selectivity over T-cell protein-tyrosine phosphatase. |
---|---|
Journal, issue, pages | J. Biol. Chem., Vol. 281, Page 8010-8015, Year 2006 |
Publish date | Jan 3, 2006 (structure data deposition date) |
Authors | Asante-Appiah, E. / Patel, S. / Desponts, C. / Taylor, J.M. / Lau, C. / Dufresne, C. / Therien, M. / Friesen, R. / Becker, J.W. / Leblanc, Y. ...Asante-Appiah, E. / Patel, S. / Desponts, C. / Taylor, J.M. / Lau, C. / Dufresne, C. / Therien, M. / Friesen, R. / Becker, J.W. / Leblanc, Y. / Kennedy, B.P. / Scapin, G. |
External links | J. Biol. Chem. / PubMed:16407290 |
Methods | X-ray diffraction |
Resolution | 2.1 - 2.2 Å |
Structure data | PDB-2fjm: PDB-2fjn: |
Chemicals | ChemComp-CL: ChemComp-073: ChemComp-MG: ChemComp-HOH: |
Source |
|
Keywords | HYDROLASE / PHOSPHATASE / SECONDARY BINDING SITE / SELECTIVITY |