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Structure paper

TitleCrystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists.
Journal, issue, pagesJ. Neurosci., Vol. 26, Page 2852-2861, Year 2006
Publish dateNov 18, 2005 (structure data deposition date)
AuthorsMayer, M.L. / Ghosal, A. / Dolman, N.P. / Jane, D.E.
External linksJ. Neurosci. / PubMed:16540562
MethodsX-ray diffraction
Resolution1.74 - 2.11 Å
Structure data

PDB-2f34:
Crystal Structure of the GluR5 Ligand Binding Core Dimer with UBP310 At 1.74 Angstroms Resolution
Method: X-RAY DIFFRACTION / Resolution: 1.74 Å

PDB-2f35:
Crystal Structure of the GluR5 Ligand Binding Core with UBP302 At 1.87 Angstroms Resolution
Method: X-RAY DIFFRACTION / Resolution: 1.87 Å

PDB-2f36:
Crystal Structure of the GluR5 Ligand Binding Core Dimer with Glutamate At 2.1 Angstroms Resolution
Method: X-RAY DIFFRACTION / Resolution: 2.11 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

ChemComp-UBA:
(S)-1-(2-AMINO-2-CARBOXYETHYL)-3(2-CARBOXYTHIOPHENE-3-YL-METHYL)-5-METHYLPYRIMIDINE-2,4-DIONE

ChemComp-HOH:
WATER

ChemComp-UBC:
(S)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE

ChemComp-SO4:
SULFATE ION

ChemComp-GLU:
GLUTAMIC ACID

Source
  • rattus norvegicus (Norway rat)
KeywordsMEMBRANE PROTEIN

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