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TitleCarbonic Anhydrase Activators. Activation of Isozymes I, II, IV, VA, VII, and XIV with L- and D-Histidine and Crystallographic Analysis of Their Adducts with Isoform II: Engineering Proton-Transfer Processes within the Active Site of an Enzyme.
Journal, issue, pagesChemistry, Vol. 12, Page 7057-7066, Year 2006
Publish dateNov 10, 2005 (structure data deposition date)
AuthorsTemperini, C. / Scozzafava, A. / Vullo, D. / Supuran, C.T.
External linksChemistry / PubMed:16807956
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-2ez7:
Carbonic anhydrase activators. Activation of isozymes I, II, IV, VA, VII and XIV with L- and D-histidine and crystallographic analysis of their adducts with isoform II: engineering proton transfer processes within the active site of an enzyme
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HG:
Unknown entry

ChemComp-ZN:
Unknown entry

ChemComp-DHI:
D-HISTIDINE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLYASE / Carbonic anhydrase II / activators

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