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TitleMolecular Basis for the Association of Microcephalin (MCPH1) Protein with the Cell Division Cycle Protein 27 (Cdc27) Subunit of the Anaphase-promoting Complex.
Journal, issue, pagesJ. Biol. Chem., Vol. 287, Page 2854-2862, Year 2012
Publish dateOct 27, 2005 (structure data deposition date)
AuthorsSingh, N. / Wiltshire, T.D. / Thompson, J.R. / Mer, G. / Couch, F.J.
External linksJ. Biol. Chem. / PubMed:22139841
MethodsX-ray diffraction
Resolution1.33 - 2.6 Å
Structure data

PDB-2etx:
Crystal Structure of MDC1 Tandem BRCT Domains
Method: X-RAY DIFFRACTION / Resolution: 1.33 Å

PDB-3t1n:
Structure of human MICROCEPHALIN (MCPH1) TANDEM BRCT domains in complex with a CDC27 phosphopeptide
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCELL CYCLE / TANDEM BRCT DOMAINS HISTONE GAMMA-H2AX / CELL CYCLE/Peptide / Tandem BRCT domains / Cell cycle regulation / DNA repair / mitosis / Phosphorylation / CELL CYCLE-Peptide complex

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