Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Journal, issue, pages	Proc. Natl. Acad. Sci. Usa, Vol. 104, Page 10022-10027, Year 2007
Publish date	Jan 23, 2007 (structure data deposition date)
Authors	Guo, R.T. / Cao, R. / Liang, P.H. / Ko, T.P. / Chang, T.H. / Hudock, M.P. / Jeng, W.Y. / Chen, C.K.-M. / Zhang, Y. / Song, Y. ...Guo, R.T. / Cao, R. / Liang, P.H. / Ko, T.P. / Chang, T.H. / Hudock, M.P. / Jeng, W.Y. / Chen, C.K.-M. / Zhang, Y. / Song, Y. / Kuo, C.J. / Yin, F. / Oldfield, E. / Wang, A.H.-J.
External links	Proc. Natl. Acad. Sci. Usa / PubMed:17535895
Methods	X-ray diffraction
Resolution	1.8 - 2.55 Å
Structure data	PDB-2e8t: S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium, FsPP and IPP Method: X-RAY DIFFRACTION / Resolution: 2.13 Å PDB-2e8u: S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and IPP (P21) Method: X-RAY DIFFRACTION / Resolution: 2.08 Å PDB-2e8v: S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with product GGPP (P21) Method: X-RAY DIFFRACTION / Resolution: 1.8 Å PDB-2e8w: S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and IPP Method: X-RAY DIFFRACTION / Resolution: 2.35 Å PDB-2e8x: S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and GPP Method: X-RAY DIFFRACTION / Resolution: 2.04 Å PDB-2e90: S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium, pyrophosphate and FPP Method: X-RAY DIFFRACTION / Resolution: 2.55 Å PDB-2e91: S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-91 Method: X-RAY DIFFRACTION / Resolution: 2.14 Å PDB-2e92: S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-261 Method: X-RAY DIFFRACTION / Resolution: 2.31 Å PDB-2e93: S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with BPH-629 Method: X-RAY DIFFRACTION / Resolution: 2.12 Å PDB-2e94: S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-364 Method: X-RAY DIFFRACTION / Resolution: 2.18 Å PDB-2e95: S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-675 Method: X-RAY DIFFRACTION / Resolution: 2.2 Å PDB-2e98: E. coli undecaprenyl pyrophosphate synthase in complex with BPH-629 Method: X-RAY DIFFRACTION / Resolution: 1.9 Å PDB-2e99: E. coli undecaprenyl pyrophosphate synthase in complex with BPH-608 Method: X-RAY DIFFRACTION / Resolution: 2 Å PDB-2e9a: E. coli undecaprenyl pyrophosphate synthase in complex with BPH-628 Method: X-RAY DIFFRACTION / Resolution: 2.1 Å PDB-2e9c: E. coli undecaprenyl pyrophosphate synthase in complex with BPH-675 Method: X-RAY DIFFRACTION / Resolution: 2.05 Å PDB-2e9d: E. coli undecaprenyl pyrophosphate synthase in complex with BPH-676 Method: X-RAY DIFFRACTION / Resolution: 2.5 Å
Chemicals	ChemComp-MG: Unknown entry ChemComp-IPE: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE ChemComp-FPS: S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE ChemComp-HOH: WATER ChemComp-GRG: GERANYLGERANYL DIPHOSPHATE ChemComp-GPP: GERANYL DIPHOSPHATE ChemComp-PPV: PYROPHOSPHATE ChemComp-FPP: FARNESYL DIPHOSPHATE ChemComp-ZOL: ZOLEDRONIC ACID / medicationYM ChemComp-M0N: (1-HYDROXY-2-IMIDAZO[1,2-A]PYRIDIN-3-YLETHANE-1,1-DIYL)BIS(PHOSPHONIC ACID) ChemComp-B29: [2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID ChemComp-364: 3-BIPHENYL-3-YL-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM ChemComp-B75: 1-HYDROXY-2-[3'-(NAPHTHALENE-2-SULFONYLAMINO)-BIPHENYL-3-YL]ETHYLIDENE-1,1-BISPHOSPHONIC ACID ChemComp-B08: (1-HYDROXY-1-PHOSPHONO-2-[1,1';3',1'']TERPHENYL-3-YL-ETHYL)-PHOSPHONIC ACID ChemComp-B28: (1-HYDROXY-1-PHOSPHONO-2-[1,1';4',1'']TERPHENYL-3-YL-ETHYL)-PHOSPHONIC ACID ChemComp-B76*: [1-HYDROXY-2-(1,1':3',1''-TERPHENYL-3-YLOXY)ETHANE-1,1-DIYL]BIS(PHOSPHONIC ACID)
Source	saccharomyces cerevisiae (brewer's yeast) escherichia coli (E. coli)
Keywords	TRANSFERASE / prenyltransferase / farnesyl pyrophosphate / bisphosphonate / cell wall / antibiotic