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Structure paper

TitleX-ray crystallographic and biochemical characterization of the inhibitory action of an imidazole-dioxolane compound on heme oxygenase
Journal, issue, pagesBiochemistry, Vol. 46, Page 1860-1867, Year 2007
Publish dateSep 6, 2006 (structure data deposition date)
AuthorsSugishima, M. / Higashimoto, Y. / Oishi, T. / Takahashi, H. / Sakamoto, H. / Noguchi, M. / Fukuyama, K.
External linksBiochemistry / PubMed:17253780
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-2dy5:
Crystal structure of rat heme oxygenase-1 in complex with heme and 2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolane
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-224:
1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
KeywordsOXIDOREDUCTASE / INHIBITOR / SUBSTRATE BOUND STRUCTURE

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