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TitleCrystal structures of DNA:DNA and DNA:RNA duplexes containing 5-(N-aminohexyl)carbamoyl-modified uracils reveal the basis for properties as antigene and antisense molecules
Journal, issue, pagesNucleic Acids Res., Vol. 35, Page 1969-1977, Year 2007
Publish dateMay 8, 2006 (structure data deposition date)
AuthorsJuan, E.C.M. / Kondo, J. / Kurihara, T. / Ito, T. / Ueno, Y. / Matsuda, A. / Takenaka, A.
External linksNucleic Acids Res. / PubMed:17341465
MethodsX-ray diffraction
Resolution1.5 - 2.3 Å
Structure data

PDB-2dp7:
Crystal Structure of D(CGCGAATXCGCG) Where X is 5-(N-aminohexyl)carbamoyl-2'-deoxyuridine
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-2dpb:
Crystal Structure of d(CGCGAATXCGCG) Where X is 5-(N-aminohexyl)carbamoyl-2'-deoxyuridine
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-2dpc:
Crystal Structure of d(CGCGAATXCGCG) Where X is 5-(N-aminohexyl)carbamoyl-2'-O-methyluridine
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-2dqo:
Crystal Structure of d(CXCTXCTTC):r(gaagaagag) Where X is 5-(N-aminohexyl)carbamoyl-2'-O-methyluridine
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-2dqp:
Structural analyses of DNA:DNA and RNA:DNA duplexes containing 5-(N-aminohexyl)carbamoyl modified uridines
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-2dqq:
Crystal Structure of d(CXCTXCTTC):r(gaagaagag) Where X is 5-(N-aminohexyl)carbamoyl-2'-O-methyluridine
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-CMY:
(6-AMINOHEXYL)CARBAMIC ACID

ChemComp-K:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-CO:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-BA:
Unknown entry

Source
  • synthetic construct (others)
KeywordsDNA / modified nucleotide / 5-(N-aminohexyl)carbamoyl-2'-deoxyuridine / B-DNA / 5-(N-aminohexyl)carbamoyl-2'-O-methyluridine / DNA-RNA HYBRID / A-form RNA:DNA hybrid duplex

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