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TitleProbing, inhibition, and crystallographic characterization of metallo-beta-lactamase (IMP-1) with fluorescent agents containing dansyl and thiol groups
Journal, issue, pagesChemmedchem, Vol. 1, Page 969-972, Year 2006
Publish dateMay 1, 2006 (structure data deposition date)
AuthorsKurosaki, H. / Yamaguchi, Y. / Yasuzawa, H. / Jin, W. / Yamagata, Y. / Arakawa, Y.
External linksChemmedchem / PubMed:16937423
MethodsX-ray diffraction
Resolution2.43 Å
Structure data

PDB-2doo:
The structure of IMP-1 complexed with the detecting reagent (DansylC4SH) by a fluorescent probe
Method: X-RAY DIFFRACTION / Resolution: 2.43 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-C4H:
N-[4-({[5-(DIMETHYLAMINO)-1-NAPHTHYL]SULFONYL}AMINO)BUTYL]-3-SULFANYLPROPANAMIDE

ChemComp-HOH:
WATER

Source
  • serratia marcescens (bacteria)
KeywordsHYDROLASE / METALLO-BETA-LACTAMASE / PROTEIN-INHIBITOR COMPLEX

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