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-Structure paper
Title | Structure of 2-deoxy-scyllo-inosose synthase, a key enzyme in the biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics, in complex with a mechanism-based inhibitor and NAD+ |
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Journal, issue, pages | Proteins, Vol. 70, Page 517-527, Year 2008 |
Publish date | Sep 20, 2005 (structure data deposition date) |
![]() | Nango, E. / Kumasaka, T. / Hirayama, T. / Tanaka, N. / Eguchi, T. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.15 - 2.3 Å |
Structure data | ![]() PDB-2d2x: ![]() PDB-2gru: |
Chemicals | ![]() ChemComp-CO: ![]() ChemComp-SO3: ![]() ChemComp-GOL: ![]() ChemComp-HOH: ![]() ChemComp-PO4: ![]() ChemComp-NAD: ![]() ChemComp-EXO: ![]() ChemComp-MPD: ![]() ChemComp-CAK: |
Source |
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![]() | LYASE / aminoglycoside / 2-deoxystreptamine / dehydroquinate synthase |