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TitleCrystal Structure of Novel NADP-dependent 3-Hydroxyisobutyrate Dehydrogenase from Thermus thermophilus HB8
Journal, issue, pagesJ. Mol. Biol., Vol. 352, Page 905-917, Year 2005
Publish dateAug 30, 2004 (structure data deposition date)
AuthorsLokanath, N.K. / Ohshima, N. / Takio, K. / Shiromizu, I. / Kuroishi, C. / Okazaki, N. / Kuramitsu, S. / Yokoyama, S. / Miyano, M. / Kunishima, N.
External linksJ. Mol. Biol. / PubMed:16126223
MethodsX-ray diffraction
Resolution1.8 - 2 Å
Structure data

PDB-1wp4:
Structure of TT368 protein from Thermus Thermophilus HB8
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2cvz:
Structure of hydroxyisobutyrate dehydrogenase from thermus thermophilus HB8
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-NDP:
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-HOH:
WATER

Source
  • thermus thermophilus (bacteria)
KeywordsOXIDOREDUCTASE / Hydroxyisobutyrate / NADP / structural genomics / RIKEN Structural Genomics/Proteomics Initiative / RSGI / valine catabolism / NADP+

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