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-Structure paper
Title | A Pharmacological Map of the Pi3-K Family Defines a Role for P110Alpha in Signaling |
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Journal, issue, pages | Cell(Cambridge,Mass. ), Vol. 125, Page 733-, Year 2006 |
Publish date | Mar 16, 2006 (structure data deposition date) |
Authors | Knight, Z.A. / Gonzalez, B. / Feldman, M.E. / Zunder, E.R. / Goldenberg, D.D. / Williams, O. / Loewith, R. / Stokoe, D. / Balla, A. / Toth, B. ...Knight, Z.A. / Gonzalez, B. / Feldman, M.E. / Zunder, E.R. / Goldenberg, D.D. / Williams, O. / Loewith, R. / Stokoe, D. / Balla, A. / Toth, B. / Balla, T. / Weiss, W.A. / Williams, R.L. / Shokat, K.M. |
External links | Cell(Cambridge,Mass. ) / PubMed:16647110 |
Methods | X-ray diffraction |
Resolution | 2.5 - 2.6 Å |
Structure data | PDB-2chw: PDB-2chx: PDB-2chz: |
Chemicals | ChemComp-039: ChemComp-HOH: ChemComp-090: ChemComp-093: |
Source |
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Keywords | TRANSFERASE/INHIBITOR / COMPLEX TRANSFERASE-INHIBITOR / PHOSPHOINOSITIDE / KINASE / LIPID / INHIBITOR / 3-KINASE / SIGNALING / QUINAZOLINONE / TRANSFERASE / TRANSFERASE-INHIBITOR complex / PHENYLTHIAZOLE |