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TitleStructures of the Hydrolase Domain of Human 10-Formyltetrahydrofolate Dehydrogenase and its Complex with a Substrate Analogue.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 62, Page 1294-, Year 2006
Publish dateJul 7, 2005 (structure data deposition date)
AuthorsKursula, P. / Schuler, H. / Flodin, S. / Nilsson-Ehle, P. / Ogg, D.J. / Savitsky, P. / Nordlund, P. / Stenmark, P.
External linksActa Crystallogr. ,Sect. D / PubMed:17057331
MethodsX-ray diffraction
Resolution1.7 - 1.85 Å
Structure data

PDB-2bw0:
Crystal Structure of the hydrolase domain of Human 10-Formyltetrahydrofolate 2 dehydrogenase
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-2cfi:
The hydrolase domain of human 10-FTHFD in complex with 6- formyltetrahydropterin
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-ZZZ:
6-FORMYLTETRAHYDROPTERIN

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / DEHYDROGENASE / NUCLEOTIDE BIOSYNTHESIS / TETRAHYDROFOLATE / FOLATE BINDING / NADP / ONE-CARBON METABOLISM / PHOSPHOPANTETHEINE

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