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TitleHydrogen Peroxide-Mediated Isoniazid Activation Catalyzed by Mycobacterium Tuberculosis Catalase-Peroxidase (Katg) and its S315T Mutant.
Journal, issue, pagesBiochemistry, Vol. 45, Page 4131-, Year 2006
Publish dateJan 16, 2006 (structure data deposition date)
AuthorsZhao, X. / Yu, H. / Yu, S. / Wang, F. / Sacchettini, J.C. / Magliozzo, R.S.
External linksBiochemistry / PubMed:16566587
MethodsX-ray diffraction
Resolution2 - 2.1 Å
Structure data

PDB-2cca:
Crystal structure of the catalase-peroxidase (KatG) and S315T mutant from Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2ccd:
Crystal structure of the catalase-peroxidase (KatG) and S315T mutant from Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsOXIDOREDUCTASE / CATALASE-PEROXIDASE / KATG / HEME / PEROXIDASE / HYDROGEN PEROXIDE / IRON / METAL-BINDING / ORGANIC RADICAL

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