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-Structure paper
Title | Structural Analysis Identifies Imidazo[1,2- B]Pyridazines as Pim Kinase Inhibitors with in Vitro Antileukemic Activity. |
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Journal, issue, pages | Cancer Res., Vol. 67, Page 6916-, Year 2007 |
Publish date | Oct 7, 2005 (structure data deposition date) |
Authors | Pogacic, V. / Bullock, A.N. / Fedorov, O. / Filippakopoulos, P. / Gasser, C. / Biondi, A. / Meyer-Monard, S. / Knapp, S. / Schwaller, J. |
External links | Cancer Res. / PubMed:17638903 |
Methods | X-ray diffraction |
Resolution | 1.9 Å |
Structure data | PDB-2c3i: |
Chemicals | ChemComp-IYZ: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE/PEPTIDE / TRANSFERASE-PEPTIDE COMPLEX / COMPLEX TRANSFERASE-PEPTIDE / PIM1 / KINASE / CANCER / LEUKEMIA / ATP-BINDING / NUCLEAR PROTEIN / NUCLEOTIDE-BINDING / PHOSPHORYLATION / PROTO- ONCOGENE / SERINE/THREONINE-PROTEIN KINASE / TRANSFERASE |