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Structure paper

TitleThree-Dimensional Structure of Human Monoamine Oxidase a (Mao A): Relation to the Structures of Rat Mao a and Human Mao B
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 102, Page 12864-, Year 2005
Publish dateJul 27, 2005 (structure data deposition date)
AuthorsDe Colibus, L. / Li, M. / Binda, C. / Lustig, A. / Edmondson, D.E. / Mattevi, A.
External linksProc. Natl. Acad. Sci. USA / PubMed:16129825
MethodsX-ray diffraction
Resolution2.2 - 3.15 Å
Structure data

PDB-2bxr:
Human Monoamine Oxidase A in complex with Clorgyline, Crystal Form A
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-2bxs:
Human Monoamine Oxidase A in complex with Clorgyline, Crystal Form B
Method: X-RAY DIFFRACTION / Resolution: 3.15 Å

PDB-2byb:
Human Monoamine Oxidase B in complex with Deprenyl
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-MLG:
N-[3-(2,4-DICHLOROPHENOXY)PROPYL]-N-METHYL-N-PROP-2-YNYLAMINE / antidepressant, inhibitor*YM

ChemComp-DPK:
DEPRENYL / inhibitor*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / NEUROTRANSMITTER / MEMBRANE-PROTEIN / FLAVIN / FAD-CONTAINING AMINE OXIDASE / MAOB ACETYLATION / FAD / FLAVOPROTEIN / MAOB / TRANSMEMBRANE NEUROTRANSMITTER

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