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-Structure paper
Title | The reversed binding of beta-phenethylamine inhibitors of DPP-IV: X-ray structures and properties of novel fragment and elaborated inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 16, Page 1744-1748, Year 2006 |
Publish date | Jun 9, 2005 (structure data deposition date) |
Authors | Nordhoff, S. / Cerezo-Galvez, S. / Feurer, A. / Hill, O. / Matassa, V.G. / Metz, G. / Rummey, C. / Thiemann, M. / Edwards, P.J. |
External links | Bioorg. Med. Chem. Lett. / PubMed:16376544 |
Methods | X-ray diffraction |
Resolution | 2.5 - 2.66 Å |
Structure data | PDB-2bua: PDB-2bub: PDB-2buc: |
Chemicals | ChemComp-NAG: ChemComp-007: ChemComp-SO4: ChemComp-HOH: ChemComp-FPB: ChemComp-008: |
Source |
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Keywords | HYDROLASE/INHIBITOR / DPP-IV / DIABETES MELLITUS / DRUG DESIGN / HYDROLASE / SERINE PROTEASE / AMINOPEPTIDASE / GLYCOPROTEIN / PROTEASE / SIGNAL- ANCHOR / TRANSMEMBRANE / COMPLEX (HYDROLASE-INHIBITOR) / HYDROLASE-INHIBITOR complex / SIGNAL-ANCHOR / COMPLEX |