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TitleDesign of new benzoxazole-2-thione-derived inhibitors of Streptococcus pneumoniae hyaluronan lyase: structure of a complex with a 2-phenylindole.
Journal, issue, pagesGlycobiology, Vol. 16, Page 757-765, Year 2006
Publish dateMay 10, 2005 (structure data deposition date)
AuthorsRigden, D.J. / Botzki, A. / Nukui, M. / Mewbourne, R.B. / Lamani, E. / Braun, S. / von Angerer, E. / Bernhardt, G. / Dove, S. / Buschauer, A. / Jedrzejas, M.J.
External linksGlycobiology / PubMed:16638841
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-2brp:
Crystal structure of S. pneumoniae hyaluronate lyase in complex with W249b
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-SIE:
SULFAMIC ACID 1-DECYL-2-(4-SULFAMOYLOXYPHENYL)-1H-INDOL-6-YL ESTER

ChemComp-XLS:
D-xylose

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • streptococcus pneumoniae (bacteria)
KeywordsLYASE / (ALFA5/ALFA5) BARREL / PEPTIDOGLYCAN-ANCHOR

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