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TitleGlycosphingolipid-Facilitated Membrane Insertion and Internalization of Cobra Cardiotoxin: The Sulfatide/Cardiotoxin Complex Structure in a Membrane-Like Environment Suggests a Lipid-Dependent Cell-Penetrating Mechanism for Membrane Binding Polypeptides.
Journal, issue, pagesJ. Biol. Chem., Vol. 281, Page 656-, Year 2006
Publish dateJan 12, 2005 (structure data deposition date)
AuthorsWang, C.-H. / Liu, J.-H. / Lee, S.-C. / Hsiao, C.-D. / Wu, W.-G.
External linksJ. Biol. Chem. / PubMed:16263708
MethodsX-ray diffraction
Resolution2.31 Å
Structure data

PDB-2bhi:
Crystal structure of Taiwan cobra cardiotoxin A3 complexed with sulfogalactoceramide
Method: X-RAY DIFFRACTION / Resolution: 2.31 Å

Chemicals

ChemComp-SFT:
SULFOGALACTOCERAMIDE

ChemComp-C10:
HEXAETHYLENE GLYCOL MONODECYL ETHER

ChemComp-HOH:
WATER

Source
  • naja atra (Chinese cobra)
KeywordsCARDIOTOXIN / COBRA CARDIOTOXIN / SULFOGALACTOCERAMIDE SULFATIDE / GLYCOSPHINGOLIPID / MEMBRANE PORE FORMATION / CYTOLYSIS

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