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Structure paper

TitleStructural analysis of strand misalignment during DNA synthesis by a human DNA polymerase
Journal, issue, pagesCell(Cambridge,Mass. ), Vol. 124, Page 331-342, Year 2006
Publish dateOct 19, 2005 (structure data deposition date)
AuthorsGarcia-Diaz, M. / Bebenek, K. / Krahn, J.M. / Pedersen, L.C. / Kunkel, T.A.
External linksCell(Cambridge,Mass. ) / PubMed:16439207
MethodsX-ray diffraction
Resolution1.65 - 2.2 Å
Structure data

PDB-2bcq:
DNA polymerase lambda in complex with a DNA duplex containing an unpaired Dtmp
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

PDB-2bcr:
DNA polymerase lambda in complex with a DNA duplex containing an unpaired Damp
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-2bcs:
DNA polymerase lambda in complex with a DNA duplex containing an unpaired Dcmp
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-2bcu:
DNA polymerase lambda in complex with a DNA duplex containing an unpaired Damp and a T:T mismatch
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-2bcv:
DNA polymerase lambda in complex with Dttp and a DNA duplex containing an unpaired Dtmp
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-PPV:
PYROPHOSPHATE

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-TTP:
THYMIDINE-5'-TRIPHOSPHATE

Source
  • homo sapiens (human)
KeywordsTransferase / Lyase/DNA / misalignment / extrahelical / mutagenesis / mutation / deletion / streisinger / slippage / Lyase-DNA COMPLEX

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