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-Structure paper
Title | Conformationally biased P3 amide replacements of beta-secretase inhibitors |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 16, Page 641-644, Year 2006 |
Publish date | Oct 7, 2005 (structure data deposition date) |
![]() | Stachel, S.J. / Coburn, C.A. / Steele, T.G. / Crouthamel, M.C. / Pietrak, B.L. / Lai, M.T. / Holloway, M.K. / Munshi, S.K. / Graham, S.L. / Vacca, J.P. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.7 - 1.8 Å |
Structure data | ![]() PDB-2b8l: ![]() PDB-2b8v: |
Chemicals | ![]() ChemComp-5HA: ![]() ChemComp-HOH: ![]() ChemComp-3BN: |
Source |
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![]() | HYDROLASE / ASPARTYL PROTEASE / BACE |