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-Structure paper
Title | Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem., Vol. 14, Page 2162-2177, Year 2006 |
Publish date | Sep 12, 2005 (structure data deposition date) |
Authors | Moretto, A.F. / Kirincich, S.J. / Xu, W.X. / Smith, M.J. / Wan, Z.K. / Wilson, D.P. / Follows, B.C. / Binnun, E. / Joseph-McCarthy, D. / Foreman, K. ...Moretto, A.F. / Kirincich, S.J. / Xu, W.X. / Smith, M.J. / Wan, Z.K. / Wilson, D.P. / Follows, B.C. / Binnun, E. / Joseph-McCarthy, D. / Foreman, K. / Erbe, D.V. / Zhang, Y.L. / Tam, S.K. / Tam, S.Y. / Lee, J. |
External links | Bioorg. Med. Chem. / PubMed:16303309 |
Methods | X-ray diffraction |
Resolution | 2 - 2.1 Å |
Structure data | PDB-2azr: PDB-2b07: |
Chemicals | ChemComp-982: ChemComp-HOH: ChemComp-598: |
Source |
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Keywords | HYDROLASE / Protein tyrosine phosphatase / Hydrolyase / Bicyclic Thiophenes / tricyclic Thiophenes |