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Structure paper

TitleStructures of microfilament destabilizing toxins bound to actin provide insight into toxin design and activity
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 102, Page 14527-14532, Year 2005
Publish dateAug 23, 2005 (structure data deposition date)
AuthorsAllingham, J.S. / Zampella, A. / D'Auria, M.V. / Rayment, I.
External linksProc. Natl. Acad. Sci. Usa / PubMed:16192358
MethodsX-ray diffraction
Resolution1.6 - 1.7 Å
Structure data

PDB-2asm:
Structure of Rabbit Actin In Complex With Reidispongiolide A
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-2aso:
Structure of Rabbit Actin In Complex With Sphinxolide B
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-2asp:
Structure of Rabbit Actin In Complex With Reidispongiolide C
Method: X-RAY DIFFRACTION / Resolution: 1.64 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-RGA:
REIDISPONGIOLIDE A

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-SPX:
SPHINXOLIDE B

ChemComp-RGC:
REIDISPONGIOLIDE C

Source
  • oryctolagus cuniculus (rabbit)
KeywordsSTRUCTURAL PROTEIN / actin / reidispongiolide a / marine macrolide / toxin / filament capping / filament severing / sphinxolide B / reidispongiolide C

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