Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Structure-Activity Relationships at the 5-Position of Thiolactomycin: An Intact (5R)-Isoprene Unit Is Required for Activity against the Condensing Enzymes from Mycobacterium tuberculosis and Escherichia coli
Journal, issue, pages	J. Med. Chem., Vol. 49, Page 159-171, Year 2006
Publish date	Aug 17, 2005 (structure data deposition date)
Authors	Kim, P. / Zhang, Y.M. / Shenoy, G. / Nguyen, Q.A. / Boshoff, H.I. / Manjunatha, U.H. / Goodwin, M.B. / Lonsdale, J. / Price, A.C. / Miller, D.J. ...Kim, P. / Zhang, Y.M. / Shenoy, G. / Nguyen, Q.A. / Boshoff, H.I. / Manjunatha, U.H. / Goodwin, M.B. / Lonsdale, J. / Price, A.C. / Miller, D.J. / Duncan, K. / White, S.W. / Rock, C.O. / Barry III, C.E. / Dowd, C.S.
External links	J. Med. Chem. / PubMed:16392800
Methods	X-ray diffraction
Resolution	2.19 - 2.3 Å
Structure data	PDB-2aq7: Structure-activity relationships at the 5-posiiton of thiolactomycin: an intact 5(R)-isoprene unit is required for activity against the condensing enzymes from Mycobacterium tuberculosis and Escherichia coli Method: X-RAY DIFFRACTION / Resolution: 2.3 Å PDB-2aqb: Structure-activity relationships at the 5-position of thiolactomycin: an intact 5(R)-isoprene unit is required for activity against the condensing enzymes from Mycobacterium tuberculosis and Escherchia coli Method: X-RAY DIFFRACTION / Resolution: 2.19 Å
Chemicals	ChemComp-TL5: (5R)-4-HYDROXY-3,5-DIMETHYL-5-[(1E,3E)-2-METHYLPENTA-1,3-DIENYL]THIOPHEN-2(5H)-ONE ChemComp-HOH: WATER ChemComp-TL6: (5R)-5-[(1E)-BUTA-1,3-DIENYL]-4-HYDROXY-3,5-DIMETHYLTHIOPHEN-2(5H)-ONE
Source	escherichia coli (E. coli)
Keywords	TRANSFERASE / FabB-ligand active-site complex