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| Title | Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors |
|---|---|
| Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 16, Page 123-128, Year 2006 |
| Publish date | Aug 2, 2005 (structure data deposition date) |
Authors | Qiao, L. / Baumann, C.A. / Crysler, C.S. / Ninan, N.S. / Abad, M.C. / Spurlino, J.C. / Desjarlais, R.L. / Kervinen, J. / Neeper, M.P. / Bayoumy, S.S. ...Qiao, L. / Baumann, C.A. / Crysler, C.S. / Ninan, N.S. / Abad, M.C. / Spurlino, J.C. / Desjarlais, R.L. / Kervinen, J. / Neeper, M.P. / Bayoumy, S.S. / Williams, R. / Deckman, I.C. / Dasgupta, M. / Reed, R.L. / Huebert, N.D. / Tomczuk, B.E. / Moriarty, K.J. |
External links | Bioorg. Med. Chem. Lett. / PubMed:16236500 |
| Methods | X-ray diffraction |
| Resolution | 2.5 Å |
| Structure data | ![]() PDB-2ajl: |
| Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-JNH: ![]() ChemComp-HOH: |
| Source |
|
Keywords | HYDROLASE / Aminopeptidase / protease / serine protease |
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homo sapiens (human)
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