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-Structure paper
Title | The discovery of fluoropyridine-based inhibitors of the Factor VIIa/TF complex. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 15, Page 4752-4756, Year 2005 |
Publish date | Jul 22, 2005 (structure data deposition date) |
![]() | Kohrt, J.T. / Filipski, K.J. / Cody, W.L. / Cai, C. / Dudley, D.A. / Van Huis, C.A. / Willardsen, J.A. / Rapundalo, S.T. / Saiya-Cork, K. / Leadley, R.J. ...Kohrt, J.T. / Filipski, K.J. / Cody, W.L. / Cai, C. / Dudley, D.A. / Van Huis, C.A. / Willardsen, J.A. / Rapundalo, S.T. / Saiya-Cork, K. / Leadley, R.J. / Narasimhan, L. / Zhang, E. / Whitlow, M. / Adler, M. / McLean, K. / Chou, Y.L. / McKnight, C. / Arnaiz, D.O. / Shaw, K.J. / Light, D.R. / Edmunds, J.J. |
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Methods | X-ray diffraction |
Resolution | 2.52 Å |
Structure data | ![]() PDB-2aei: |
Chemicals | ![]() ChemComp-CA: ![]() ChemComp-CAC: ![]() ChemComp-03R: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / BLOOD COAGULATION / SERINE PROTEASE / THROMBOSIS / GLA / PYRIDINE / BENZAMIDINE / TISSUE FACTOR / COFACTOR / ENZYME INHIBITOR COMPLEX |