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TitleStructure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A.
Journal, issue, pagesNat. Struct. Biol., Vol. 4, Page 57-63, Year 1997
Publish dateJun 23, 1996 (structure data deposition date)
AuthorsRaves, M.L. / Harel, M. / Pang, Y.P. / Silman, I. / Kozikowski, A.P. / Sussman, J.L.
External linksNat. Struct. Biol. / PubMed:8989325
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-1vot:
ACETYLCHOLINESTERASE (E.C. 3.1.1.7) COMPLEXED WITH HUPERZINE A
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-2ace:
NATIVE ACETYLCHOLINESTERASE (E.C. 3.1.1.7) FROM TORPEDO CALIFORNICA
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-HUP:
Huperzine A

ChemComp-HOH:
WATER

ChemComp-ACH:
ACETYLCHOLINE

Source
  • torpedo californica (Pacific electric ray)
KeywordsHYDROLASE / NEUROTRANSMITTER CLEAVAGE / SERINE HYDROLASE / CATALYTIC TRIAD / ALPHA/BETA HYDROLASE

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