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-Structure paper
Title | Crystal Structures of the Main Peptidase from the SARS Coronavirus Inhibited by a Substrate-like Aza-peptide Epoxide |
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Journal, issue, pages | J. Mol. Biol., Vol. 353, Page 1137-1151, Year 2005 |
Publish date | Jun 30, 2005 (structure data deposition date) |
Authors | Lee, T.-W. / Cherney, M.M. / Huitema, C. / Liu, J. / James, K.E. / Powers, J.C. / Eltis, L.D. / James, M.N. |
External links | J. Mol. Biol. / PubMed:16219322 |
Methods | X-ray diffraction |
Resolution | 1.88 - 2.3 Å |
Structure data | PDB-2a5a: PDB-2a5i: PDB-2a5k: |
Chemicals | ChemComp-CL: ChemComp-EDO: ChemComp-HOH: ChemComp-AZP: ChemComp-GOL: |
Source |
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Keywords | HYDROLASE / cysteine peptidase / 3C-like / N-finger / chymotrypsin-like fold / long loop / alpha-helical domain / dimer / catalytic dyad / specificity pockets / aza-peptide epoxide / substrate-like inhibitor / C-S covalent bond / epoxide stereochemistry |