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-Structure paper
| Title | Identification of AMPD2 allosteric inhibitors with novel mechanism of action by fragment merging approach. |
|---|---|
| Journal, issue, pages | Slas Discov, Vol. 42, Page 100313-100313, Year 2026 |
| Publish date | May 19, 2026 (structure data deposition date) |
Authors | Yamanaka, K. / Uhara, T. / Nomura, A. / Akaki, T. / Adachi, T. / Kitao, Y. / Hantani, Y. |
External links | Slas Discov / PubMed:42177948 |
| Methods | X-ray diffraction |
| Resolution | 2.5 Å |
| Structure data | ![]() PDB-26xc: |
| Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-PO4: ![]() ChemComp-ES9: ![]() ChemComp-SO4: |
| Source |
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Keywords | METAL BINDING PROTEIN / AMP deaminase / hydrolase / purine metabolism / zinc / allosteric regulation |
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