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TitleThe X ray Analysis of the Complexes of Carbonic Anhydrase II in complex with 1,3-Oxazole-Containing Sulfonamide Derivatives Elucidating the Structural Basis for Exceptionally High Inhibitory Potency.
Journal, issue, pagesTo Be Published
Publish dateFeb 12, 2026 (structure data deposition date)
AuthorsStoliarskaia, M.Y. / Nikonov, O.S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-23om:
Crystal Structure Analysis of Bovine Carbonic Anhydrase II to 5-(2-morpholin-4-ylcarbonyl-1,3-oxazol-5-yl)thiophene-2-sulfonamide.
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-8V5:
5-(2-morpholin-4-ylcarbonyl-1,3-oxazol-5-yl)thiophene-2-sulfonamide

ChemComp-BOG:
octyl beta-D-glucopyranoside / detergent*YM

ChemComp-GOL:
GLYCEROL

ChemComp-ZN:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • bos taurus (domestic cattle)
KeywordsLYASE / Carbonic anhydrase / CARBOHYDRATE

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