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TitleA crystallographic and spectroscopic study of the complex between d(CGCGAATTCGCG)2 and 2,5-bis(4-guanylphenyl)furan, an analogue of berenil. Structural origins of enhanced DNA-binding affinity.
Journal, issue, pagesBiochemistry, Vol. 35, Page 5655-5661, Year 1996
Publish dateAug 8, 1995 (structure data deposition date)
AuthorsLaughton, C.A. / Tanious, F. / Nunn, C.M. / Boykin, D.W. / Wilson, W.D. / Neidle, S.
External linksBiochemistry / PubMed:8639524
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-227d:
A CRYSTALLOGRAPHIC AND SPECTROSCOPIC STUDY OF THE COMPLEX BETWEEN D(CGCGAATTCGCG)2 AND 2,5-BIS(4-GUANYLPHENYL)FURAN, AN ANALOGUE OF BERENIL. STRUCTURAL ORIGINS OF ENHANCED DNA-BINDING AFFINITY
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-BGF:
2,5-BIS(4-GUANYLPHENYL)FURAN

ChemComp-HOH:
WATER

KeywordsDNA / B-DNA / DOUBLE HELIX / COMPLEXED WITH DRUG

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