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-Structure paper
Title | Two classes of p38alpha MAP kinase inhibitors having a common diphenylether core but exhibiting divergent binding modes. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 15, Page 5274-5279, Year 2005 |
Publish date | Jun 10, 2005 (structure data deposition date) |
![]() | Michelotti, E.L. / Moffett, K.K. / Nguyen, D. / Kelly, M.J. / Shetty, R. / Chai, X. / Northrop, K. / Namboodiri, V. / Campbell, B. / Flynn, G.A. ...Michelotti, E.L. / Moffett, K.K. / Nguyen, D. / Kelly, M.J. / Shetty, R. / Chai, X. / Northrop, K. / Namboodiri, V. / Campbell, B. / Flynn, G.A. / Fujimoto, T. / Hollinger, F.P. / Bukhtiyarova, M. / Springman, E.B. / Karpusas, M. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2 Å |
Structure data | ![]() PDB-1zyj: ![]() PDB-1zz2: |
Chemicals | ![]() ChemComp-BOG: ![]() ChemComp-BI5: ![]() ChemComp-HOH: ![]() ChemComp-B11: |
Source |
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![]() | TRANSFERASE / PROTEIN-INHIBITOR COMPLEX |