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-Structure paper
Title | Identification of potent and selective MMP-13 inhibitors |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 15, Page 4105-4109, Year 2005 |
Publish date | May 27, 2005 (structure data deposition date) |
Authors | Wu, J. / Rush III, T.S. / Hotchandani, R. / Du, X. / Geck, M. / Collins, E. / Xu, Z.B. / Skotnicki, J. / Levin, J.I. / Lovering, F.E. |
External links | Bioorg. Med. Chem. Lett. / PubMed:16005220 |
Methods | X-ray diffraction |
Resolution | 2 Å |
Structure data | PDB-1ztq: |
Chemicals | ChemComp-ZN: ChemComp-CA: ChemComp-033: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / MMPs / METALLOPROTEASE / MMP-13 / COLLAGENASE / ZINC CHELATOR / hydroxamate / hydrophobic S1' / P1' group |