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Structure paper

TitleReconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids.
Journal, issue, pagesJ. Biol. Chem., Vol. 280, Page 32921-32929, Year 2005
Publish dateMay 10, 2005 (structure data deposition date)
AuthorsXie, C. / Prahl, A. / Ericksen, B. / Wu, Z. / Zeng, P. / Li, X. / Lu, W.Y. / Lubkowski, J. / Lu, W.
External linksJ. Biol. Chem. / PubMed:15894545
MethodsX-ray diffraction
Resolution1.15 - 1.5 Å
Structure data

PDB-1zmh:
Crystal structure of human neutrophil peptide 2, HNP-2 (variant Gly16-> D-Ala)
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-1zmi:
Crystal structure of human alpha_defensin-2 (variant GLY16->D-ALA), P 32 2 1 space group )
Method: X-RAY DIFFRACTION / Resolution: 1.15 Å

PDB-1zmk:
Crystal structure of human alpha-defensin-2 (variant Gly16-> D-ALA), P 42 21 2 space group
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-P6G:
HEXAETHYLENE GLYCOL / precipitant*YM

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

Source
  • homo sapiens (human)
KeywordsANTIMICROBIAL PROTEIN / alpha-defensin / D-amino acid substitution / ANTIMICROBIAL / D-amino acid substitutions

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